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Chromosome testing (Next Generation Sequencing)

What is pre-implantation genetic testing with next generation sequencing?

Next generation sequencing is a pre-implantation genetic testing technique that screens all 24 chromosomes in a developing embryo, enabling our scientists to select only embryos with a normal chromosome profile to transfer.

There is no waiting list to access chromosome testing at IVFAustralia.

Who is next generation sequencing suitable for?

Chromosome testing by next generation sequencing is suited for couples or individuals where:

  • The woman is aged 38 or older
  • There is a history of recurrent miscarriage
  • There has been repeated IVF failure, for example 5 or more embryos have been replaced without success
  • There has previously been a chromosomally abnormal pregnancy (eg Down syndrome)

What is the process of chromosome testing by next generation sequencing?

Chromosome testing by next generation sequencing involves taking a few cells from a developing embryo for testing.

Next generation sequencing amplifies the DNA from the cell’s nucleus by multiplying it thousands of times before being placed on a microarray, or DNA chip, where it is compared with normal male and female DNA.

This allows the scientists to accurately detect chromosomal errors, so only an embryo with a normal chromosome profile is selected for transfer, increasing the chance of a successful pregnancy.

While the majority of biopsies are undertaken on Day 5 embryos, we have the flexibility to undertake the biopsy on any day during embryo development depending on the patient’s individual circumstances.

PGT process to screen for chromosomal abnormalities

Is PGT with next generation sequencing always accurate?

Chromosomal testing by next generation sequencing is 95% accurate. This means that having a normal test result makes it highly likely that a resulting child will not have any chromosomal abnormality. However we strongly recommend that all our patients who conceive following pre-implantation genetic testing go through the normal process of antenatal testing.

How much does PGT with next generation sequencing cost?

An IVF cycle with pre-implantation genetic testing has three components of cost:

  • The cost of the IVF cycle
  • The cost of the hospital stay
  • The cost of the PGT technology

At IVFAustralia the cost of pre-implantation genetic testing with next generation sequencing is $700 per embryo biopsied with a maximum fee of $3995 for 6 or more embryos from a single IVF cycle.

There is no Medicare rebate associated with PGT. However, your final costs may vary depending on your individual circumstances.

If you have any questions about the cost of pre-implantation genetic testing with IVF Australia please phone 18000 111 483 or email us.

Read more about the cost of IVF >

What more information?

If you would like to know more about pre-implantation genetic testing with IVFAustralia please book an appointment with a fertility specialist or call 1800 111 483.

Find out the costs of next generation sequencing...
Learn more about chromosomal abnormalities...
Contact us about chromosome testing with next generation sequencing...

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